Synthesis and spectral characteristics of hydrazinocarbonothioyl derivatives of maleopimaric acid

Abstract

Reaction of acyl isothiocyanates of 2-allyl- and 2-benzylmaleopimarimides with 3-carboxy- and 2,4-dinitrophenylhydrazines and hydrazides of some aromatic acids (benzoic, 4-hydroxy- and 4-methoxybenzoic, nicotinic, isonicotinic) furnished linear hydrazinocarbonothioyl derivatives of these maleopimarimides in high yields. Structure of the synthesized compounds was determined by 1H,13C, 1H-13C HSQC, 1H-13C HMBC, COSY, NOESY, and 1H-15N HMBC NMR spectroscopy methods.