Synthesis and Spectral Characteristics of Hydrazinocarbonothioyl Derivatives of Maleopimaric Acid

Abstract

Reaction of acyl isothiocyanates of 2-allyl- and 2-benzylmaleopimarimides with 3-carboxy- and 2,4-dinitrophenylhydrazines and hydrazides of some aromatic acids (benzoic, 4-hydroxy- and 4-methoxybenzoic, nicotinic, isonicotinic) furnished linear hydrazinocarbonothioyl derivatives of these maleopimarimides in high yields. Structure of the synthesized compounds was determined by 1H,13C, 1H–13C HSQC, 1H–13C HMBC, COSY, NOESY, and 1H–15N HMBC NMR spectroscopy methods.