Synthesis and Spectral Characteristics of Quinoline Derivatives of Maleopimaric Acid

Abstract

The reaction of maleopimaric acid and its acid chloride with 3-, 6-, and 8-aminoquinolines afforded quinoline containing maleopimarimides and carboxamides in high yields, respectively. Structure of the synthesized compounds was determined by 1Н, 13С, 1H–13C HSQC, 1H–13C HMBC, COSY, NOESY, and 1Н–15N HMBC NMR spectroscopy methods.