JOURNAL ARTICLE
TP53TG1 enhances cisplatin sensitivity of non-small cell lung cancer cells through regulating miR-18a/PTEN axis
Huijuan XiaoYihe LiuPan LiangBo WangHongna TanYonggao ZhangXianzheng GaoJianbo Gao
Year: 2018 Journal: Cell & Bioscience Vol: 8 (1)Pages: 23-23 Publisher: BioMed Central
Abstract
TP53TG1 increased the sensitivity of NSCLC cells to cisplatin by modulating miR-18a/PTEN axis, elucidating a novel approach to boost the effectiveness of chemotherapy for NSCLC.
Keywords:
Cisplatin PTEN A549 cell Apoptosis Flow cytometry MTT assay Viability assay Cancer research Cell growth Transfection Biology Chemistry Cell culture Molecular biology PI3K/AKT/mTOR pathway Chemotherapy Biochemistry
Metrics
71
Cited By
3.89
FWCI (Field Weighted Citation Impact)
29
Refs
0.94
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
Cancer-related molecular mechanisms research
Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research
MicroRNA in disease regulation
Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research
RNA modifications and cancer
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
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