GAS5 knockdown reduces the chemo-sensitivity of non-small cell lung cancer (NSCLC) cell to cisplatin (DDP) through regulating miR-21/PTEN axis

Lin Cao; Jia Chen; Baiqing Ou; Cuizhong Liu; Yan Zou; Qiong chen

doi:10.1016/j.biopha.2017.06.089

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GAS5 knockdown reduces the chemo-sensitivity of non-small cell lung cancer (NSCLC) cell to cisplatin (DDP) through regulating miR-21/PTEN axis

Lin Cao Jia Chen Baiqing Ou Cuizhong Liu Yan Zou Qiong chen

Year: 2017 Journal: Biomedicine & Pharmacotherapy Vol: 93 Pages: 570-579 Publisher: Elsevier BV

DOI: 10.1016/j.biopha.2017.06.089

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Keywords:

PTEN GAS5 Tensin Cancer research Cisplatin Gene knockdown Lung cancer microRNA Cell growth Biology Downregulation and upregulation Medicine Oncology Internal medicine PI3K/AKT/mTOR pathway Chemotherapy Apoptosis Long non-coding RNA Gene

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Cancer-related molecular mechanisms research

Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research

RNA modifications and cancer

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Circular RNAs in diseases

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

GAS5 knockdown reduces the chemo-sensitivity of non-small cell lung cancer (NSCLC) cell to cisplatin (DDP) through regulating miR-21/PTEN axis

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