JOURNAL ARTICLE
LncRNA MEG3 enhances cisplatin sensitivity in non-small cell lung cancer by regulating miR-21-5p/SOX7 axis
Pei WangDong ChenHongbing MaYong Li
Year: 2017 Journal: OncoTargets and Therapy Vol: Volume 10 Pages: 5137-5149 Publisher: Dove Medical Press
Abstract
MEG3 overexpression induced DDP sensitivity of NSCLC cells by regulating miR-21-5p/SOX7 axis, shedding light on the molecular mechanism of MEG3 involved in the development of DDP resistance of NSCLC cells.
Keywords:
Cisplatin Sensitivity (control systems) Cancer research Lung cancer MEG3 Medicine Oncology Internal medicine Chemistry Downregulation and upregulation Engineering Long non-coding RNA Electronic engineering Biochemistry Chemotherapy Gene
Metrics
117
Cited By
6.76
FWCI (Field Weighted Citation Impact)
43
Refs
0.98
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
Cancer-related molecular mechanisms research
Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research
Circular RNAs in diseases
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
RNA modifications and cancer
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
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