This chapter explores the way business technology strategies are leveraged by organizations to fuel real, informed decisions and sustainable competitive advantages. The discussion is built on core business processes around data analytics, artificial intelligence, cloud computing, and automation for fueling agility, operational efficiency. Businesses have invested in technology as a strategic enabler of its daily activities, but it is now enabling businesses to gain foresight; understand market trends, to be able to offer unique experiences for their customers and make supply chains better. The following will discuss important matters about dit alignment towards achieving business objectives-and emerging technologies to realize competitive advantage in the marketplace. The chapter will document real-world case studies and best practices on how technology is applied by organizations to change business models, to disrupt industries, and to create competitive advantage and enable innovation. At the end of this chapter, readers will see how technology has to play a role in its ability.