Limonoids\nand Triterpenoids from <i>Dysoxylum\nmollissimum</i> var. <i>glaberrimum</i>

Abstract

Seven new limonoids, dysomollides\nA–G (<b>1</b>–<b>7</b>), and two new cycloapotirucallane-type\ntriterpenoids, dysomollins\nA and B (<b>8</b> and <b>9</b>), together with three known\ncompounds, dysoxylumin A (<b>10</b>) and toonapubesins A (<b>11</b>) and B (<b>12</b>), were isolated from the twigs\nof <i>Dysoxylum mollissimum</i> var. <i>glaberrimum</i>. The structures of <b>1</b>–<b>9</b> were elucidated\non the basis of spectroscopic methods. Compound <b>10</b> showed\ninhibitory activity against A549 cells with an IC₅₀ value\nof 2.1 μM, and compound <b>11</b> exhibited activity against\nP388 cells with an IC₅₀ value of 6.7 μM.