Single-Atom Pt Boosting Electrochemical Nonenzymatic\nGlucose Sensing on Ni(OH)₂/N-Doped Graphene

Abstract

Conventional\nnanomaterials in electrochemical nonenzymatic sensing\nface huge challenge due to their complex size-, surface-, and composition-dependent\ncatalytic properties and low active site density. In this work, we\ndesigned a single-atom Pt supported on Ni­(OH)₂ nanoplates/nitrogen-doped\ngraphene (Pt₁/Ni­(OH)₂/NG) as the first example\nfor constructing a single-atom catalyst based electrochemical nonenzymatic\nglucose sensor. The resulting Pt₁/Ni­(OH)₂/NG\nexhibited a low anode peak potential of 0.48 V and high sensitivity\nof 220.75 μA mM^–1 cm^–2 toward\nglucose, which are 45 mV lower and 12 times higher than those of Ni­(OH)₂, respectively. The catalyst also showed excellent selectivity\nfor several important interferences, short response time of 4.6 s,\nand high stability over 4 weeks. Experimental and density functional\ntheory (DFT) calculated results reveal that the improved performance\nof Pt₁/Ni­(OH)₂/NG could be attributed to stronger\nbinding strength of glucose on single-atom Pt active centers and their\nsurrounding Ni atoms, combined with fast electron transfer ability\nby the adding of the highly conductive NG. This research sheds light\non the applications of SACs in the field of electrochemical nonenzymatic\nsensing.