Derek D. WrightMichelle M. JarvieBenjamin SouthwellCarmen KincaidJudy A. WestrickS. Sameera PereraDavid P. EdwardsRobert B. Cody
With the recent legalization of cannabis in multiple jurisdictions and widespread use as a medical treatment, there has been an increased focus on product safety and the potential impacts of contaminants on human health. One factor that has received little attention is the possible exposure to potentially hazardous levels of toxic elements from rolling (smoking) papers. The elemental composition of rolling papers is largely unregulated, with a minority of jurisdictions regulating papers only when they are part of a final cannabis product. This study reports the concentrations of 26 elements in commercially available rolling papers and estimates potential maximum exposures relative to USP232 and ICH Q3D dosages in pharmaceutical compounds. Exposure estimates indicate that the concentrations of several elements in some products, particularly Cu, Cr, and V, may present a potential hazard to frequent users. Several elements, including Ag, Ca, Ba, Cu, Ti, Cr, Sb, and possibly others, are likely present in elevated quantities in some papers due to product design and manufacturing processes. Our results further suggest that Cu-based pigments are used by a number of manufacturers and that regular use of these products might result in exposures as high as 4.5-11 times the maximum exposure limits. Further research to quantify the contribution of rolling papers to elemental exposure under realistic smoking conditions is warranted.
Derek Wright (3212361)Michelle M. Jarvie (18417055)Benjamin Southwell (18417058)Carmen Kincaid (18417061)Judy Westrick (14161346)S. Sameera Perera (4264912)David Edwards (5663)Robert B. Cody (1540579)
M. V. PeńkinSergei F. BoulygaB. DabbsDiane M FischerM. A. HumphreyA. L. KochetkovA. KoepfMartina Burnik Šturm
Silvia JakabováIvona JančoMarek ŠnircJozef GolianIva Juranović CindrićJúlius Árvay
Eleni C. PappaEfthymia KondyliAthanasios C. PappasLida PapalamprouAndrea MaraPanagiota KyriakakiEvangelos ZoidisAgori KarageorgouElisavet GiamouriAikaterini SarriPanagiotis SimitzisMichael GoliomytisGavino SannaEleni TsiplakouConstantinos A. Georgiou