Multi-walled Carbon Nanotubes-Aminate Reduced Graphene Oxide Modified Glassy Carbon Electrode as the Voltammetric Sensor for Sensitive Electrochemical Determination of Rutin

Abstract

In this paper, a highly sensitive voltammetric method for determination of rutin is developed using multi-walled carbon nanotubes-aminate reduced graphene oxide (MWCNTs/ARGO) modified electrode. The incorporated ARGO served as dispersing agent and conductive sheet, which could effectively prevented aggregation of MWCNTs. Compared with either MWCNTs or ARGO, the hybrid nanomaterials showed a strong synergistic effect between two materials and exhibited higher activity for the electro-oxidation of rutin. MWCNTs/ARGO composite was characterized by scanning electron microscope (SEM) and electrochemical impedance spectroscopy (EIS). Under the optimized conditions, MWCNTs/ARGO modified electrode exhibited wide linear range from 0.01 to 112 μM with the detection limit of 2 nM (S/N = 3). Moreover, the proposed method was successfully applied to determine rutin in compound rutin tablets and satisfactory results were obtained.