JOURNAL ARTICLE

2-Amino-4-(2-chlorophenyl)-6-(naphthalen-1-yl)pyridine-3-carbonitrile

Wei HongxiaJing ZhuMing LiJianqiang WangGuo Cheng

Year: 2012 Journal:   Acta Crystallographica Section E Structure Reports Online Vol: 68 (6)Pages: o1839-o1839   Publisher: International Union of Crystallography

Abstract

In the title compound, C 22 H 14 ClN 3 , prepared by a one-pot reaction under microwave irradiation, the dihedral angles between the central pyridine ring and the pendant naphthyl and chlorobenzene ring systems are 49.2 (2) and 58.2 (3)°, respectively. In the crystal, inversion dimers linked by pairs of N—H...N hydrogen bonds generate R 2 2 (8) loops. The pyridine N atom is the acceptor.

Keywords:
Pyridine Dihedral angle Ring (chemistry) Chlorobenzene Chemistry Hydrogen bond Acceptor Microwave irradiation Crystal structure Nitrogen atom Crystal (programming language) Crystallography Medicinal chemistry Stereochemistry Molecule Organic chemistry Physics Catalysis

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Topics

Synthesis and biological activity
Physical Sciences →  Chemistry →  Organic Chemistry
Synthesis of Organic Compounds
Health Sciences →  Medicine →  Pharmacology
Multicomponent Synthesis of Heterocycles
Physical Sciences →  Chemistry →  Organic Chemistry

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