A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of <i>c-MYC</i> G-quadruplex DNA

Marco Deiana; Karam Chand; Ján Jamroškovič; Rabindra Nath Das; Ikenna Obi; Erik Chorell; Nasim Sabouri

doi:10.1039/d0nr03404e

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A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA

Marco Deiana Karam Chand Ján Jamroškovič Rabindra Nath Das Ikenna Obi Erik Chorell Nasim Sabouri

Year: 2020 Journal: Nanoscale Vol: 12 (24)Pages: 12950-12957 Publisher: Royal Society of Chemistry

DOI: 10.1039/d0nr03404e

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Abstract

A self-assembled light-up rotor probe with outstanding sensitivity and selectivity for the c-MYC promoter G-quadruplex DNA is reported.

Keywords:

G-quadruplex DNA Rotor (electric) Selectivity Sensitivity (control systems) Chemistry Nanotechnology Combinatorial chemistry Materials science Biochemistry Engineering

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DNA and Nucleic Acid Chemistry

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Advanced biosensing and bioanalysis techniques

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

RNA Interference and Gene Delivery

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA

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