&lt;p&gt;Mesoporous silica nanoparticles as a delivery system for improving antiangiogenic therapy&lt;/p&gt;

Jianguo Sun; Qin Jiang; Xiao‐Pei Zhang; K. Y. Shan; Bai-Hui Liu; Chen Zhao; Biao Yan

doi:10.2147/ijn.s195504

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JOURNAL ARTICLE

Mesoporous silica nanoparticles as a delivery system for improving antiangiogenic therapy

Jianguo Sun Qin Jiang Xiao‐Pei Zhang K. Y. Shan Bai-Hui Liu Chen Zhao Biao Yan

Year: 2019 Journal: International Journal of Nanomedicine Vol: Volume 14 Pages: 1489-1501 Publisher: Dove Medical Press

DOI: 10.2147/ijn.s195504

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Abstract

This study provides a novel strategy of encapsulating bevacizumab to protect and deliver it, which could increase the time between administration and formulation shelf-life. MSN-encapsulated bevacizumab is a promising drug delivery alternative of antiangiogenic therapy.

Keywords:

Bevacizumab In vivo Mesoporous silica Drug delivery Pharmacology Cytotoxicity Angiogenesis Neovascularization Vascular endothelial growth factor In vitro Materials science Chemistry Medicine Nanotechnology Cancer research Chemotherapy Mesoporous material Biochemistry Surgery Biology

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Angiogenesis and VEGF in Cancer

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Nanoplatforms for cancer theranostics

Physical Sciences → Engineering → Biomedical Engineering

Nanoparticle-Based Drug Delivery

Physical Sciences → Materials Science → Biomaterials

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<p>Mesoporous silica nanoparticles as a delivery system for improving antiangiogenic therapy</p>

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