Prepubertal children seem to need more bolus insulin for meals than calculated from the 500 rule, especially at breakfast, but less insulin for corrections than calculated from the 100 rule. Two to 3 hours seems to be the appropriate range for DIA in this age group.
Miriam Sanahuja VidalJosé Conesa Ballestero
Genoveva Sastre VilarrasaMontserrat Marimon