Gold Nanoparticles Covered Hollow SiO<sub>2</sub>Nanocapsules for DOX Delivery and Multiple Antitumor

Guanru Chang; Yuhua Shen; Chun Pei; Long Chen

doi:10.1051/matecconf/20166701013

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JOURNAL ARTICLE

Gold Nanoparticles Covered Hollow SiO₂Nanocapsules for DOX Delivery and Multiple Antitumor

Guanru Chang Yuhua Shen Chun Pei Long Chen

Year: 2016 Journal: MATEC Web of Conferences Vol: 67 Pages: 01013-01013 Publisher: EDP Sciences

DOI: 10.1051/matecconf/20166701013

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Abstract

A chemo and photothermal therapy integrated nanoplatform, DOX-loaded and AuNPs-covered hollow SiO2 nanocapsules (Au-HMSN@DOX), were constructed for enhanced cancer therapy via sequential NIR irradiation. HMSN are used as nanocarriers for drug delivery. AuNPs exhibit an outstanding photothermal effect for increasing the local temperature. Compared with HMSN@DOX, the combination of NIR light-triggered photothermal of AuNPs and Chemotherapy of DOX leads to enhanced antitumor effect and reduced side effect.

Keywords:

Photothermal therapy Nanocapsules Nanocarriers Photothermal effect Doxorubicin Drug delivery Nanoparticle Colloidal gold Nanotechnology Materials science Cancer therapy Chemotherapy Chemistry Cancer Medicine

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Nanoplatforms for cancer theranostics

Physical Sciences → Engineering → Biomedical Engineering

Advanced Nanomaterials in Catalysis

Physical Sciences → Materials Science → Materials Chemistry

Gold and Silver Nanoparticles Synthesis and Applications

Physical Sciences → Materials Science → Electronic, Optical and Magnetic Materials

Gold Nanoparticles Covered Hollow SiO₂Nanocapsules for DOX Delivery and Multiple Antitumor

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