JOURNAL ARTICLE
Design, synthesis and evaluation of rivastigmine and curcumin hybrids as site-activated multitarget-directed ligands for Alzheimer’s disease therapy
Yujie LiPeng PengLi TangYunzhen HuYongzhou HuRong Sheng
Year: 2014 Journal: Bioorganic & Medicinal Chemistry Vol: 22 (17)Pages: 4717-4725 Publisher: Elsevier BV
Keywords:
Chemistry Curcumin Rivastigmine Butyrylcholinesterase Carbamate Cholinesterase IC50 ABTS Aché Acetylcholinesterase Hydrolysate In vitro Stereochemistry Pharmacology Biochemistry Antioxidant Enzyme Donepezil
Metrics
50
Cited By
4.00
FWCI (Field Weighted Citation Impact)
37
Refs
0.93
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
Cholinesterase and Neurodegenerative Diseases
Health Sciences → Medicine → Pharmacology
Alzheimer's disease research and treatments
Health Sciences → Medicine → Physiology
Curcumin's Biomedical Applications
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Medicine
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