Enantioselective Metal‐Free Hydrogenation Catalyzed by Chiral Frustrated Lewis Pairs

Abstract

Frustration is key: Enantioselective hydrogenation under metal-free conditions by using frustrated Lewis pair (FLP) catalysts is a significant breakthrough for catalytic hydrogenation, which is dominated by chiral transition-metal catalysts. This success demonstrates the potential of FLP chemistry for the synthesis of valuable chiral compounds by means of metal-free catalytic hydrogenation.