JOURNAL ARTICLE
Multifunctional 3-Schiff base-4-hydroxycoumarin derivatives with monoamine oxidase inhibition, anti-β-amyloid aggregation, metal chelation, antioxidant and neuroprotection properties against Alzheimer's disease
Zhimin WangSai‐Sai XieXuemei LiJia‐Jia WuXiaobing WangLing-Yi Kong
Year: 2015 Journal: RSC Advances Vol: 5 (86)Pages: 70395-70409 Publisher: Royal Society of Chemistry
Abstract
These 3-Schiff base-4-hydroxycoumarin derivatives were multifunctional agents with monoamine oxidase inhibition, anti-β-amyloid aggregation, metal chelation, antioxidant and neuroprotection properties against Alzheimer's disease.
Keywords:
Monoamine oxidase Neuroprotection Chemistry Chelation Antioxidant Schiff base Monoamine oxidase B Amyloid (mycology) Monoamine neurotransmitter Biochemistry Pharmacology Stereochemistry Organic chemistry Enzyme Medicine Receptor Inorganic chemistry Serotonin
Metrics
22
Cited By
2.10
FWCI (Field Weighted Citation Impact)
56
Refs
0.87
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
Cholinesterase and Neurodegenerative Diseases
Health Sciences → Medicine → Pharmacology
Alzheimer's disease research and treatments
Health Sciences → Medicine → Physiology
Computational Drug Discovery Methods
Physical Sciences → Computer Science → Computational Theory and Mathematics
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