JOURNAL ARTICLE

Current trends of Alzheimer’s Disease Management and Future Prospects

Joshi, AbhilashRath, Akash KumarMishra, Sujit Kumar

Year: 2021 Journal:   OPAL (Open@LaTrobe) (La Trobe University)   Publisher: La Trobe University

Abstract

ABSTRACT Alzheimer’s disease (AD) is a widely known neurodegenerative disarray and the most common cause of dementia. It mostly causes due to deteriorating nerve tissues in brain. Study shows people with age of 65 and more; often shows signs of dementia, for which they are suffering in various ways. Different health issues, habits of diet, by genetic inheritance and due to progressing age commonly generate risks of AD in a person. Alzheimer’s disease is a problem which is not from any particular region. Patients worldwide are suffering and in search of better cure from Alzheimer’s disease. In this article, we have discussed about how inhibitors of Acetylcholinesterase (ACHE), Amyloid Beta (Aβ), Beta-secretase-1 (BACE1), Phosphodiesterase 4D (PDE4D) and N-methyl-D-aspartate (NMDA) are helping in prevention of Dementia or AD. Beside this, some other therapies for AD have also been discussed in this review.

Keywords:
Disease Dementia Inheritance (genetic algorithm) Life expectancy Disease management Degenerative disease

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Topics

Phosphodiesterase function and regulation
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology
Pharmacology and Nanomedicine Research
Life Sciences →  Pharmacology, Toxicology and Pharmaceutics →  Drug Discovery
Biological Research and Disease Studies
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology

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