The prognostic value of IDH mutations and MGMT promoter status in secondary high-grade gliomas
Juratli, T.Kirsch, M.Geiger, K.Souceck, S.Schackert, G.Krex, D.
Abstract
Objective: Reports about the prognostic value of IDH mutations and the promoter region of the O6-Methyl-guanyl-methyl-transferase (MGMT) gene in secondary high-grade gliomas (sHGG) are few in number. We analyzed the relationships among histology, IDH mutations, MGMT promoter status, treatment and outcome[for full text, please go to the a.m. URL]
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