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<p>Time-dependent receiver operating characteristic (ROC) curves and area under the curve (AUC) estimates at 6 months (red) and 12 months post-enrollment. Panel A: ROC for MMP2 with time-to-death endpoint. Panel B: ROC for MMP8 with time-to-death endpoint. Panel C: ROC for TIMP1 with time-to-death endpoint. Panel D: ROC for MMP8 with composite time to absolute decline in FVC ≥10%, death, or lung transplant endpoint. Panel E: ROC for MMP9 with composite endpoint. Panel F: ROC for TIMP1 with composite endpoint.</p> <p>(PDF)</p>
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Jerome FanSuneel UpadhyeAndrew Worster