JOURNAL ARTICLE

Transdermal Patches: Advancements, Challenges And Future Perspectives

Hemamalini Saravanan*, K. L. Senthil Kumar

Year: 2024 Journal:   Zenodo (CERN European Organization for Nuclear Research)   Publisher: European Organization for Nuclear Research

Abstract

Introduction Transdermal drug delivery systems have gained prominence in recent years as a non-invasive and effective means of administering therapeutics. Among these systems, transdermal patches have emerged as a versatile platform offering sustained and controlled drug release. This abstract explores the mechanisms, formulation strategies, recent advancements, challenges and future prospects of transdermal patches, providing insights into their potential for revolutionizing drug delivery. Methodology This narrative review was conducted through an extensive search of published articles and literature databases to gather information on transdermal patch technology. Peer-reviewed articles, reviews, and regulatory guidelines were analyzed to elucidate the current state of transdermal patch research and development. Emphasis was placed on recent advancements, formulation strategies, regulatory considerations and future perspectives to provide a comprehensive overview of the field. Conclusion Transdermal patches offer a promising avenue for enhancing drug delivery efficiency and patient compliance. Despite facing challenges such as limited drug permeability and regulatory hurdles, recent advancements in formulation technologies and wearable devices have propelled the field forward. The integration of nanotechnology, smart materials, and personalized medicine approaches holds great potential for optimizing transdermal patch design and efficacy. By addressing current limitations and embracing emerging technologies, researchers and clinicians can harness the full potential of transdermal patches to improve therapeutic outcomes and patient quality of life.

Keywords:
Transdermal Transdermal patch Narrative review Wearable computer Skin barrier Drug

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