Self-Healing,\nElectrically Conductive, Antibacterial,\nand Adhesive Eutectogel Containing Polymerizable Deep Eutectic Solvent\nfor Human Motion Sensing and Wound Healing

Abstract

Flexible electronic devices such as wearable sensors\nare essential\nto advance human–machine interactions. Conductive eutectogels\nare promising for wearable sensors, despite their challenges in self-healing\nand adhesion properties. This study introduces a multifunctional eutectogel\nbased on a novel polymerizable deep eutectic solvent (PDES) prepared\nby the incorporation of diallyldimethylammonium chloride (DADMAC)\nand glycerol in the presence of polycyclodextrin (PCD)/dopamine-grafted\ngelatin (Gel-DOP)/oxidized sodium alginate (OSA). The synthesized\neutectogel has reversible Schiff-base bonds, hydrogen bonds, and host–guest\ninteractions, which enable rapid self-healing upon network disruption.\nGPDO-15 eutectogel has significant tissue adhesion, high stretchability\n(419%), good ionic conductivity (0.79 mS·cm^–1), and favorable antibacterial and self-healing properties. These\neutectogels achieve 90% antibacterial effect, show excellent biocompatibility,\nand can be used as sensors to monitor human activities with strong\nstability and durability. The <i>in vivo</i> studies indicate\nthat the eutectogels can improve the wound healing process which makes\nthem an effective option for biological dressings.