Additional file 1 of A novel delivery nanobiotechnology: engineered miR-181b exosomes improved osteointegration by regulating macrophage polarization

Abstract

Additional file 1: Figure S1. The identification of hBM-MSC. Figure S2. Exo-181b inhibited the inflammatory response by enhancing M2 polarization macrophages of BMDMs in vitro. Figure S3. The inhibition of PRKCD enhanced M2 polarization of BMDMs of Exo-181b. Figure S4. The sustained release profile of Exo by hydrogel. Figure S5. Exo-181b have no direct improvement on the proliferation, migration and osteogenic differentiation of hBM-MSCs in vitro. Figure S6. The microCT analysis of the in vivo experiment. Table S1. Primer sequences used in qRT-PCR