The modern supply chain is a complex network of interconnected processes involving procurement,manufacturing, warehousing, logistics, and distribution. With increasing globalization, heightened customerexpectations, and fluctuating market demands, traditional supply chain models often struggle to maintainefficiency and cost-effectiveness. Artificial Intelligence (AI) has emerged as a transformative force, offering robustcapabilities for optimizing supply chain operations. This paper explores the integration of AI technologies such asmachine learning, predictive analytics, computer vision, natural language processing, and autonomous systemsinto various stages of the supply chain. The study highlights how AI enhances demand forecasting, inventorymanagement, route optimization, supplier evaluation, risk management, and customer satisfaction. Furthermore,it discusses real-world applications, benefits, challenges, and future trends in AI-driven supply chain optimization.By leveraging data-driven insights and intelligent automation, AI is redefining supply chain strategies to be moreagile, resilient, and responsive to market dynamics while significantly reducing operational costs.