Synthesis of tetrahydropyridines by one-pot multicomponent reaction using nano-sphere silica sulfuric acid

Shiri, Morteza; Masoume Daraei; Zolfigol, Mohammad Ali; Fateme Derakhshan‑Panah; Kruger, Hendrik Gerhardus; Mokhlesi, Mohammad

doi:10.6084/m9.figshare.13330811

JOURNAL ARTICLE

Synthesis of tetrahydropyridines by one-pot multicomponent reaction using nano-sphere silica sulfuric acid

Shiri, Morteza Masoume Daraei Zolfigol, Mohammad Ali Fateme Derakhshan‑Panah Kruger, Hendrik Gerhardus Mokhlesi, Mohammad

Year: 2020

DOI: 10.6084/m9.figshare.13330811

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Abstract

A highly efficient protocol for the synthesis of 1,2,3,4-tetrahydropyridines in the presence of nano-sphere silica sulfuric acid (NS-SSA) was used for good yields by one-pot multicomponent reaction (MCRs). The reagent nano-sphere silica sulfuric acid (NS-SSA) has several advantages, such as easy workup, nontoxicity, convenience and high yields of products.

Keywords:

Sulfuric acid Reagent Reaction conditions Catalysis Reaction mechanism

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Physical Sciences → Chemistry → Organic Chemistry

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Physical Sciences → Chemistry → Organic Chemistry

Synthesis of tetrahydropyridines by one-pot multicomponent reaction using nano-sphere silica sulfuric acid

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