Bioinspired\nAdhesive Hydrogel Driven\nby Adenine and Thymine

Abstract

Bioinspired\nstrategies have drawn much\nattention for designing intelligent hydrogels with promising performance.\nHerein, we present a bioinspired adhesive hydrogel driven by adenine\nand thymine, which are the basic units of DNA. The adhesive hydrogel\nexhibited promising adhesive property for the surface of various solid\nmaterials, including muscle tissues, plastics, rubbers, glasses, metals,\nceramics, carnelians, and woods. The maximum peeling strength of hydrogels\nwas 330 N m^–1 on aluminum, superior to that of PAAm\nhydrogels with 70 N m^–1. The strong adhesive behavior\nremained more than 30 times repeated peeling tests. Moreover, the\nswelling behavior, morphological structure, mechanical strength, and\npeeling adhesive strength were also investigated and confirmed the\nformation and various characteristics of adhesive hydrogels driven\nby adenine and thymine. Thus, the biomimetic strategy to design promising\nadhesive hydrogels can provide various opportunities in tissue engineering,\nsuch as wound dressing, bioglues, and tissue adhesives.