The rise of multi-tenant Software-as-a-Service (SaaS) platforms has significantly transformed enterprise computing models, allowing for cost efficiency, global scalability, and rapid deployment. However, this evolution also introduces sophisticated cybersecurity risks, particularly within platforms like Salesforce, which supports mission-critical CRM processes. Zero Trust Architecture (ZTA), as codified by NIST SP 800-207, offers a robust security framework that is particularly well-suited for dynamic, cloud-native, multi-tenant environments. This paper provides a technically detailed examination of how ZTA principles can be operationalized within Salesforce using platform-native controls such as Hyperforce, Salesforce Shield, and Event Monitoring, in conjunction with external security fabric integrations. We evaluate real-world implementation architectures, threat modeling techniques, telemetry ingestion pipelines, and policy enforcement mechanisms. Our findings suggest that a layered Zero Trust strategy that spans identity, data, network, and behavioral analytics delivers a resilient security posture that is both scalable and compliant.