IMPACTO DO USO PROLONGADO DE ALPRAZOLAM EM PACIENTES COM SÍNDROME DO PÂNICO

Abstract

ABSTRACT Panic Disorder is a debilitating psychiatric condition that affects a significant portion of the population, causing a major impact on patients’ quality of life. Alprazolam is a medication widely used in the treatment of this disorder, especially due to its anxiolytic properties. Objective: To analyze the impacts of prolonged alprazolam use in patients diagnosed with panic disorder, considering its effects on therapeutic efficacy, safety, and long-term clinical outcomes. Methodology: This study was developed as a literary review, with research conducted in databases such as PubMed, BVS, and SCIELO, covering the period from 2013 to 2024, with articles published in Portuguese and English. Results: Studies indicate that alprazolam is effective in reducing panic symptoms in the short term, but its prolonged use is associated with the development of dependence, cognitive adverse effects, and difficulties in managing anxiety in the long term. Conclusion: Alprazolam use can be beneficial in the treatment of panic disorder, especially in acute situations, but its prolonged use should be carefully monitored to minimize the risks of dependence and cognitive damage. Keywords: Panic disorder, alprazola/m, dependence, adverse effects, pharmacological treatment.