Sedation in Pediatric Patients Undergoing Magnetic Resonance Imaging: An Observational Comparison

Abstract

Background: This study aimed to compare sedation methods in pediatric patients undergoing mag-netic resonance imaging (MRI) using three different anesthetic agents (sevoflurane, thiopental, and propofol) regarding safety, efficacy, time management, and side effects. Materials and Methods: An observational study was conducted with 126 pediatric patients divided into three groups, each receiving one of the three sedative agents: Group S (n = 43), Group T (n = 41), and Group P (n = 42). Patients in Group S received induction with 8% sevoflurane, Group T received 5 mg kg1 of thiopental intravenously, and Group P received 2 mg kg-1 of propofol intrave-nously, followed by maintenance via infusion. Results: The mean age was 37.3 ± 2 months. Cranial MRI was most frequently requested (64.5%). Group P had higher desaturation (p = 0.029) and respiratory depression (p = 0.008) rates. Group T had the shortest induction time (p <0.001), while Group S showed the fastest wake-up times (p = 0.002; p = 0.001). Conclusions: Sevoflurane is distinguished by its rapid emergence from sedation and low incidence of side effects. Thiopental has a quick induction time, whereas propofol is associated with minimal agitation but higher respiratory complications. These findings can guide clinicians in selecting the most appropriate sedation method for pediatric MRI.