Enhanced Electrochemical Performance Using Polyaniline/BiPr Composite Nanosheet-modified Glassy Carbon Electrode

Abstract

Background: L-cysteine (L-CySH) plays a crucial physiological role in the life-support system, which has been widely applied in the food and medicine industries. Abnormal content of LCySH in the human body can lead to liver damage, Alzheimer';s disease, and even cancer. Therefore, it is of great practical importance to investigate highly sensitive and selective methods for the determination of L-CySH. Methods: L-CySH electrochemical detection by cyclic voltammetry (CV) technique was reported using the polyaniline/BiPr composite nanosheet-modified glassy carbon electrode (GCE). objective: Polyaniline/BiPr composite nanosheets modified glassy carbon electrode (GCE) was used for L-cysteine (L-CySH) electrochemical detection by cyclic voltammetry (CV) technique. Results: The obtained nanosheets with a size of less than 500 nm were composed of rhombohedral Bi1.35Pr0.65O3, tetragonal Bi2O3, and hexagonal Pr2O3. Irregular polyaniline nanoparticles were covered on BiPr nanosheets. Polyaniline/BiPr composite nanosheet-modified GCE had good electrocatalytic performance for L-CySH detection. A pair of CV peaks was observed on the BiPr composite nanosheet-modified GCE with the potentials at +0.06 V and –0.75 V. Peak potentials at the polyaniline/ BiPr composite nanosheet-modified GCE were shifted to –0.09 V and –0.72 V. The linear range detection limit indicated 0.0005–2 mM and 0.086 µM for the polyaniline/BiPr composite nanosheet-modified GCE. Conclusion: Polyaniline/BiPr composite nanosheets provide a kind of new electrode material for improving the electrochemical performance towards L-CySH determination.