JOURNAL ARTICLE

Cuproptosis-related signature predicts prognosis and indicates tumor immune infiltration in bladder cancer

Haoyue ShengJianhua GuYongqiang HuangDamian KołatGuo-Hai ShiLihua YanDingwei Ye

Year: 2024 Journal:   Translational Andrology and Urology Vol: 13 (10)Pages: 2280-2293   Publisher: AME Publishing Company

Abstract

Our study sheds light on the biological functions of CPRGs within the TME of BLCA and their correlations with clinical parameters and patient prognosis. The identification of distinct molecular clusters with varying prognoses and immune cell infiltrations highlights the heterogeneity of BLCA and underscores the potential of CPRGs as biomarkers for prognosis and therapeutic targets. These findings offer new perspectives for the development of immunotherapeutic strategies in the treatment of BLCA patients, potentially leading to more personalized and effective cancer therapies.

Keywords:
Bladder cancer Infiltration (HVAC) Immune system Signature (topology) Medicine Bladder tumor Oncology Pathology Internal medicine Cancer Immunology Mathematics Materials science

Metrics

1
Cited By
1.25
FWCI (Field Weighted Citation Impact)
28
Refs
0.74
Citation Normalized Percentile
Is in top 1%
Is in top 10%

Citation History

Topics

Bladder and Urothelial Cancer Treatments
Health Sciences →  Medicine →  Surgery
Ferroptosis and cancer prognosis
Health Sciences →  Medicine →  Pulmonary and Respiratory Medicine
Cancer Immunotherapy and Biomarkers
Health Sciences →  Medicine →  Oncology

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