Design of a PIT biosensor based on plasmonic-graphene-black phosphorous hybrid for hypercholesterolemia detection

Abstract

Cardiovascular diseases are the primary and fundamental reasons of people death around the world. Precise, fast responding, compact and integrable biosensors are considered as the most important prevention or treatment devices. In this work, remarkable absorbers based on graphene-plasmonic-black phosphorous hybrid structures are proposed. These devices are utilized for bio-sensing applications. The presented device is consisted of different quarter-cylindrical and plate shaped layers of graphene, black phosphorous, Ag, Au and Al₂O₃. In order to improve functionality of the presented absorber (improving the absorption's peak value), effects of structural parameters and chemical potential (E_f) on the absorption spectrum are being considered. The proposed structure will be considered as a biosensor for detection of cholesterol concentrations in blood samples (this would help physicians in diagnosis of hypercholesterolemia and prevention of cardiovascular diseases), after improving its characteristics. Finally, it is expected for this biosensor the following remarkable sensitivity, figure of merit, quality factor and detection limit of 6045.6 nm/RIU, 237.61 RIU^{- 1}, (80.3-90.1) and (2.1e-4-2.26e-5) RIU, respectively. Therefore, the proposed device can be an appropriate candidate for bio-sensing applications in optical integrated circuits.