Binaphthyl-based chiral covalent organic frameworks for chiral drug separation

Hui‐Chao Ma; Haiping Jiang; Zi-Hui Yao; Junfeng Tan; Yang‐Yang Xing; Gong-Jun Chen; Yu‐Bin Dong

doi:10.1039/d4cc02028f

ScienceGate Book Chapters

JOURNAL ARTICLE

Binaphthyl-based chiral covalent organic frameworks for chiral drug separation

Hui‐Chao Ma Haiping Jiang Zi-Hui Yao Junfeng Tan Yang‐Yang Xing Gong-Jun Chen Yu‐Bin Dong

Year: 2024 Journal: Chemical Communications Vol: 60 (76)Pages: 10580-10583 Publisher: Royal Society of Chemistry

DOI: 10.1039/d4cc02028f

Get Full-Text PDF Get Analytical Report

Abstract

A novel binaphthyl-based chiral (R)-BHTP-COF was synthesized that can serve as an efficient CSP for HPLC. The COF-packed HPLC columns provide high resolution, selectivity, and durability for the chiral separation of six racemic drugs.

Keywords:

Covalent bond Chemistry Drug Combinatorial chemistry Separation (statistics) Stereochemistry Organic chemistry Pharmacology Computer science Medicine

Metrics

Cited By

1.69

FWCI (Field Weighted Citation Impact)

Refs

0.85

Citation Normalized Percentile

Is in top 1%

Is in top 10%

Citation History

Topics

Covalent Organic Framework Applications

Physical Sciences → Materials Science → Materials Chemistry

Metal-Organic Frameworks: Synthesis and Applications

Physical Sciences → Chemistry → Inorganic Chemistry

Luminescence and Fluorescent Materials

Physical Sciences → Materials Science → Materials Chemistry

Binaphthyl-based chiral covalent organic frameworks for chiral drug separation

Abstract

Metrics

Citation History

Topics

Related Documents

Chiral covalent organic frameworks for asymmetric catalysis and chiral separation

Recent Advances of Covalent Organic Frameworks for Chiral Separation

Construction of dual-chiral covalent organic frameworks for enantioselective separation

Recent advances of chiral covalent organic frameworks for enantiomer separation

Chiral induction in covalent organic frameworks