MoSe2 nanosheets-based sensor for electrochemical detection of dopamine, ascorbic acid, and uric acid

Abstract

Abstract There has been a growing interest in the field of transition metal dichalcogenide (TMD) materials and their potential applications in the field of electrochemical sensors. In the present work, molybdenum diselenide (MoSe 2 ), as a typical representative of TMD, was prepared using a facile hydrothermal method and characterized in terms of its morphological and structural properties. Then, the obtained MoSe 2 was dispersed in various solvents to investigate its electrocatalytic properties towards dopamine (DA), ascorbic acid (AA), and uric acid (UA). The electrochemical measurements revealed that deionized water is an effective solvent to disperse the MoSe 2 and modify electrodes with the MoSe 2 for electrochemical applications. Furthermore, the glassy carbon electrode (GCE) modified with the MoSe 2 , referred as GCE-MoSe 2 , was used as an electrochemical sensor to simultaneously detect the DA, AA, and UA. The GCE-MoSe 2 exhibited wide linear detection with concentration ranges of 1–333 µM for DA, 50–3440 µM for AA, and 5–1146 µM for UA in phosphate buffer solution and low detection limits (LODs) of 0.57 µM, 13.7 µM, and 1.75 µM, respectively. The electrode further displayed good selectivity, reproducibility, and stability. This work provides valuable insights on constructing electrochemical sensing devices with high analytical performance using the important two-dimensional (2D) TMD materials.