G<sub>4</sub>-Hemin-loaded 2D nanosheets for combined and targeted chemo-photodynamic cancer therapy

Gowtham Raj; Tamraparni Ghosh; D. S. Vasudev; P. Harsha; Devu B. Kumar; J. Laxmi Prasad; V. B. Athul; S Abhimanyu; Reji Varghese

doi:10.1039/d4nr01494d

JOURNAL ARTICLE

G₄-Hemin-loaded 2D nanosheets for combined and targeted chemo-photodynamic cancer therapy

Gowtham Raj Tamraparni Ghosh D. S. Vasudev P. Harsha Devu B. Kumar J. Laxmi Prasad V. B. Athul S Abhimanyu Reji Varghese

Year: 2024 Journal: Nanoscale Vol: 16 (34)Pages: 16195-16203 Publisher: Royal Society of Chemistry

DOI: 10.1039/d4nr01494d

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Abstract

A supramolecular strategy for the fabrication of a PDT-active 2D nanosheet loaded with a POD-mimicking DNAzyme for the synergetic combination of PDT and CDT for targeted cancer therapy is reported.

Keywords:

Nanosheet Photodynamic therapy Hemin Cancer therapy Nanotechnology Materials science Cancer Targeted therapy Cancer research Supramolecular chemistry Chemistry Medicine Internal medicine Biochemistry Heme Crystallography Enzyme

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Nanoplatforms for cancer theranostics

Physical Sciences → Engineering → Biomedical Engineering

Advanced biosensing and bioanalysis techniques

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Luminescence and Fluorescent Materials

Physical Sciences → Materials Science → Materials Chemistry

G₄-Hemin-loaded 2D nanosheets for combined and targeted chemo-photodynamic cancer therapy

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