The transmembrane protease TMPRSS2 as a potential target for treatment of virus infection

Abstract

TMPRSS2 is a member of the Type II Transmembran Serine Proteases (TTSPs) family, a critical tool for coronavirus and influenza virus entry into host cells [1][2][3].Here, we outline the essential role of the host serine protease TMPRSS2 in virus infection and focus on the development strategy of some potent inhibitors of TMPRSS2. . .