EZH2 Promotes Multiple Myeloma Progression via STAT3 Pathway Activation

Yanyu Wang; Jing Tian; Dan Huang; Yuan Gao; Huan Lin; Lejia Liu; Aixin Wang

doi:10.24976/discov.med.202436183.68

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JOURNAL ARTICLE

EZH2 Promotes Multiple Myeloma Progression via STAT3 Pathway Activation

Yanyu Wang Jing Tian Dan Huang Yuan Gao Huan Lin Lejia Liu Aixin Wang

Year: 2024 Journal: Discovery Medicine Vol: 36 (183)Pages: 721-721 Publisher: Discovery Medicine

DOI: 10.24976/discov.med.202436183.68

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Abstract

The effect of EZH2 and STAT3 pathways on MM regulation was revealed and verified. EZH2 promoted the progression of MM cells by activating the STAT3 pathway. The EZH2 and STAT3 pathways could be potential targets for effective MM treatment.

Keywords:

Multiple myeloma EZH2 Cancer research STAT3 Chemistry Signal transduction Cell biology Medicine Biology Internal medicine Gene Histone Biochemistry

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Epigenetics and DNA Methylation

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

MicroRNA in disease regulation

Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research

EZH2 Promotes Multiple Myeloma Progression via STAT3 Pathway Activation

Abstract

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