A Bispecific Dendritic-T cell Engager Induces Potent Antitumor Immunity

JOURNAL ARTICLE

Year: 2024 Journal: Cancer Discovery Publisher: American Association for Cancer Research

DOI: 10.1158/2159-8290.cd-rw2024-019

Abstract

Major Finding: A bispecific dendritic cell (DC)–T cell engager (BiCE) was developed that facilitates cDC1-CD8+ PD-1+ T-cell physical interactions.

Keywords:

Immunity Cancer research T cell Dendritic cell Chemistry Cell biology Biology Computational biology Immune system Immunology

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