Antibacterial Activity of Zn Decorated TiO2 Nanocomposites

Abstract

Bacterial infections have a significant public health impact. Infections are caused by bacteria in animals, plants as well as humans. Pathogenic bacteria can produce toxins, which are chemical poisons that interfere with cell function such as digestion of normal human enzymes, evasion of infection-fighting white blood cells, and immune clearance. Antibiotic prophylaxis is used to prevent bacterial infection. Antibiotic resistance is one of the most serious concerns in world health. Antibacterial nanoparticles are one possible answer to antimicrobial resistance. These nanomaterials not only kill antibiotic-resistant bacteria through various modes of action but, they can also be employed in conjunction with existing clinically relevant antibiotics to help overcome antimicrobial resistance mechanisms. In this study, anodized titanium dioxide (TiO2 ) nanorods were treated hydrothermally with zinc oxide (ZnO) nanoparticles to give titanium (Ti) antibacterial properties. The antibacterial activity of synthesized samples was investigated by Agar Well Diffusion method at 40 mg/ml concentration, against gram negative Klebsiella pneumoniae. To determine the antibacterial activity, the diameter of the zone of inhibition was measured, and the resulting data were statistically analyzed. Zn/TiO2 nano particles were characterized by using X-ray diffraction (XRD) Analysis.