Smart sweat glucose detection system based on organic electrochemical transistor and near field communication

Abstract

A smart glucose detection system based on organic electrochemical transistor and near field communication module was built to detect sweat sample. The system mainly consists of three parts: glucose sensor, electrochemical detection module and application. The basic three electrodes (gate, source and drain) were prepared by screen printing technology on the polyethylene terephthalate sheets selected as the substrate material. The gate electrode was multilayer modified with gold membrane, Prussian Blue and glucose oxidase, and the channel between the source and drain electrodes was covered with a poly (3,4-ethylenedioxythiophene): poly (styrenesulfonate) film. The potential drop caused by the redox reaction of glucose on the gate electrode changed the response of source-drain current signal. The electrochemical detection module with near field communication function was customized to realize the functions of signal detection, amplification and data transmission. Conjunct with smart Android devices analyzed and processed the data stream from near field communication to display glucose test result. The high sensitivity attributed to the amplification function of the field effect device and high selectivity to the enzyme sensor realize the detection of glucose in simulated sweat, which paves the way to relevant glucose detection in diabetics without the need for invasive finger-stick blood sampling.