Non-enzymatic electrochemical glucose sensing using nickel-based catalysts

Abstract

This study investigates the use of nickel-based catalysts for non-enzymatic electrochemical glucose sensing, a promising alternative to traditional enzymatic methods. The primary objective is to evaluate the effectiveness, sensitivity, and practicality of these catalysts in detecting glucose concentrations. Utilizing a novel approach in synthesizing and integrating nickel-based catalysts into an electrochemical sensor setup, this research aims to enhance the sensitivity and response time while maintaining selectivity against potential interferences commonly found in biological samples. The study encompasses the fabrication of the sensor, calibration against various glucose concentrations, and rigorous testing under different conditions to mimic real-world scenarios. The results demonstrate the sensor's capability in terms of sensitivity, specificity, and stability, showing a significant improvement over traditional enzymatic sensors. The findings suggest a viable pathway for developing more efficient, cost-effective, and robust glucose monitoring systems, which could have substantial implications in diabetes management and other healthcare applications. The study also identifies areas for further research and potential enhancements in the technology.