Electrochemical Dopamine-Imprinted Sensor Based on Tio2 Nanoparticles and Polypyrrole-Chitosan Composites Modified Glassy Carbon Electrode

Abstract

In this study, a composite material containing PY and CTS, as functional material, and dopamine, as template, was electrodeposited onto a GCE surface modified with NP from TiO2.The prepared MIP sensor was characterized by CV, SEM, FTIR and UV-vis techniques.The developed MIP matrix was used for dopamine detection, using DPV method.Diverse analytical parameters were optimized, such as: monomer, template, SE concentrations, electropolymerization cycles, pH medium, incubation time and scan rate.In the best conditions, the sensor response to dopamine was linear, in the concentration range from 1 x 10 -6 to 1 x 10 -5 mol/L -1 .LOD was about 2.81.10 -7 mol/L -1 , and sensitivity was 3.202 μA/L/mol -1 /cm -2 .Furthermore, the proposed MIP sensor showed good selectivity, repeatability, reproducibility and stability.Also, it was successfully applied for dopamine determination in urine samples.