Microalgal Nanocarrier Drug Delivery in Cancer Therapy

Abstract

A suitable treatment plan is needed for cancer, a common medical condition.Chemotherapy also radiation are the two majorly common therapeutic modalities for the treatment of cancer; yet, serious side effects have been linked to these therapies.Radiation, for instance, can negatively impact a patient's immune system function.By offering cutting-edge corrective remedies, these adverse effects may be reduced.Microalgae also contain various types of bioactive molecules, including carotenoids, different kinds of polysaccharides, vitamins, sterols, fibers, minerals, etc. Considerable advancement in the creation of anti-malignant medications may be made possible by the vast amount of unused biomass found in microalgae and their excellent diversity of chemical components.Previously, this property of microalgal biodiversity was used for profit to produce dietary supplements and gelling agents.However, recently, several studies aimed at examining the possible anti-carcinogenic activity of microalgal extracts came to the majority of conclusions that they could induce programmed cancer cell death on either caspase-dependent or independent routes.Diatoms are unicellular photosynthetic creatures that are highly productive and have short growth cycles.They are important for the biogeochemical cycling of nitrogen, carbon, and silica.The bio-silica of diatoms has the potential to be a successful medication administration for targeted cancer remedial treatment because of its, biodegradability, bio-compatibility, nano-porosity, and substantial surface area.In this review work, we have talked about the many microphytal species that have athwart tumor activity and the tumor cell lines that have been modified using microalgal extracts that have been found to have an inhibitory effect on cell cycle and proliferation.