Multifunctional protein-based self-assembled nanoplatform: overcoming hypoxic tumor microenvironment for enhanced imaging-guided photodynamic therapy

Min Li; Ziyi Cheng; Heng Liu; Kun Dou; Huan Xiao; Linlu Zhao; Fabiao Yu

doi:10.1039/d3bm01130e

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Multifunctional protein-based self-assembled nanoplatform: overcoming hypoxic tumor microenvironment for enhanced imaging-guided photodynamic therapy

Min Li Ziyi Cheng Heng Liu Kun Dou Huan Xiao Linlu Zhao Fabiao Yu

Year: 2023 Journal: Biomaterials Science Vol: 11 (20)Pages: 6881-6893 Publisher: Royal Society of Chemistry

DOI: 10.1039/d3bm01130e

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Abstract

A protein-based self-assembled nanoplatform (CAT-I-BODIPY NPs) has been developed with in situ oxygen-supplementation for enhanced PDT.

Keywords:

Photodynamic therapy Tumor microenvironment Chemistry In situ BODIPY Hypoxia (environmental) Cancer research Biophysics Nanotechnology Tumor cells Oxygen Medicine Materials science Fluorescence Biology

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Topics

Nanoplatforms for cancer theranostics

Physical Sciences → Engineering → Biomedical Engineering

Photodynamic Therapy Research Studies

Health Sciences → Medicine → Pulmonary and Respiratory Medicine

Cancer, Hypoxia, and Metabolism

Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research

Multifunctional protein-based self-assembled nanoplatform: overcoming hypoxic tumor microenvironment for enhanced imaging-guided photodynamic therapy

Abstract

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