Pyridine‐Regulated Lamellar Nickel‐Based Metal–Organic Framework (Ni‐MOF) for Nonenzymatic Electrochemical Glucose Sensor

Abstract

Abstract 2D metal–organic frameworks (MOFs) are considered as promising electrochemical sensing materials and have attracted a lot of attention in recent years. Compared with bulk MOFs, the construction of 2D MOFs can increase the exposure of active sites by obtaining a larger surface area ratio. Herein, a facile one‐pot hydrothermal synthesis of pyridine‐regulated lamellar Ni‐MOFs with ultrathin and well‐defined 2D morphology is described. Compared with the bulk structure, the 2D lamellar Ni‐MOF has higher surface area and active site density, showing better electrochemical glucose sensing performance. The 2D lamellar Ni‐MOF exhibits a fast amperometric response of less than 3 s and a high sensitivity of 907.54 µA m m −1 cm −2 toward glucose with a wide linear range of 0.5–2665.5 µ m . Furthermore, the 2D lamellar Ni‐MOF also possesses excellent stability and reproducibility, and can be used to detect glucose with high accuracy and reliability in different environments.