Electrochemical Behaviors of Norepinephrine on the Silver Doped Poly Aminosulfonic Acid Composite Membrane Modified Electrode and its Determination

Abstract

The Ag-poly aminosulfonic acid composite membrane modified glassy carbon electrode (GCE) was fabricated by cyclic voltammery. The membrane had excellent properties for catalyzing the redox of norepinephrine (NE) and excluding the interference of ascorbic acid for the reductive of NE. The reductive peak currents of NE were linear with its concentrations in the range of 8.49 × 10-7 ~ 7.55 × 10-6 mol/L and 7.55 × 10-6 ~10-4 mol/L. The detection limit was 5.66 × 10-8 mol/L (S/N = 3). The conditions, such as pH values, scan rates and the influence of foreign substances, that affected the determination of NE were investigated. The proposed method had wide linear range, high sensitivity and good selectivity and was used for detecting the content of the NE in injections with satisfied results.