Simultaneous Voltammetric Determination of Norepinephrine, Uric Acid and Folic Acid at the Surface of Modified Chloranil Carbon Nanotube Paste Electrode

Abstract

The electrochemical behavior of norepinephrine (NE) is investigated on the surface of a carbon-paste electrode modified with chloranile (CA) and carbon nanotubes. The prepared modified electrode showed an efficient catalytic role in the electrochemical oxidation of NE, leading to remarkable decrease in oxidation overpotential and enhancement of the kinetics of the electrode reaction. Differential pulse voltammetric peak currents of NE increased linearly with its concentrations at the range of 0.03 μM to 500 μM and the detection limit (3σ) was determined to be 11.2 nM. This modified electrode exhibits well-separated oxidation peaks for NE, uric acid (UA) and folic acid (FA). The modified electrode is successfully applied for the accurate determination of NE, UA and FA in some real samples.