JOURNAL ARTICLE

Identification and Validation of Anoikis-Related Signatures for Predicting Prognosis in Lung Adenocarcinoma with Machine Learning

Qilong WangNannan SunMingzhi Zhang

Year: 2023 Journal:   International Journal of General Medicine Vol: Volume 16 Pages: 1833-1844   Publisher: Dove Medical Press

Abstract

Our anoikis-related signature from RNA-seq data may be a novel prognostic biomarker in patients with LUAD. It may help physicians develop personalized LUAD treatments in clinical practice. Moreover, ITGB4 may affect the development of LUAD through the oxidative phosphorylation pathway.

Keywords:
Anoikis Lasso (programming language) Proportional hazards model Medicine Univariate Adenocarcinoma Immunohistochemistry Oncology KEGG Cancer Metastasis Bioinformatics Cancer research Internal medicine Pathology Multivariate statistics Transcriptome Biology Gene expression Gene Machine learning Genetics

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Citation History

Topics

Ferroptosis and cancer prognosis
Health Sciences →  Medicine →  Pulmonary and Respiratory Medicine
Cancer-related molecular mechanisms research
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Cancer Research
RNA modifications and cancer
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology
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